Flawed trials, flawed analysis: why CBP should avoid rating itself.

Value and limitation of meta-analysis.

Meta-analysis is a valuable method of aggregating data sets of different trials which are inadequate or unconvincing on their own. There are strict rules on the retrieval and selection of data which are crucial in terms of the validity of a meta-analysis. Many so-called meta-analyses are flawed because of lack of a protocol or non adherence to it. Also underreporting of clinical trials is haunt...

The Flawed Reasoning Behind Johnson v. United States and a Solution: Why a Facts-Based Approach Should Have Been Used to Interpret the Residual Clause of the Armed Career Criminal Act

Response to: Pre-referral rectal artesunate in severe malaria: a flawed trial

A response to and comment on Pre-referral rectal artesunate in severe malaria: a flawed trial, by Karim F Hirji and Zulfiqarali G Premji.

Wireless Ad-hoc Networks

Deployed in 1990’s, Mobile Ad-hoc networks have been widely researched for many years. Mobile Ad-hoc Networks are a collection of two or more devices equipped with wireless communications and networking capability. These devices can communication with other nodes that immediately within their radio range or one that is outside their radio range. For the later, the nodes should deploy an interme...

Bias resulting from the use of 'assay sensitivity' as an inclusion criterion for meta-analysis.

Assay sensitivity has been proposed as a criterion for including psychiatric clinical outcome studies in meta-analyses. The authors assess the performance of assay sensitivity as a method for determining study appropriateness for meta-analysis by calculating expected standard drug vs placebo effect sizes for various combinations of high quality and flawed studies. In the absence of flawed studi...